| dc.contributor.advisor |
Kafka, Stanislav
|
|
| dc.contributor.author |
Pokoj, Petr
|
|
| dc.date.accessioned |
2013-10-07T21:06:03Z |
|
| dc.date.available |
2013-10-07T21:06:03Z |
|
| dc.date.issued |
2012-02-10 |
|
| dc.identifier |
Elektronický archiv Knihovny UTB |
cs |
| dc.identifier.uri |
http://hdl.handle.net/10563/22084
|
|
| dc.description.abstract |
V práci je popsána metoda konverze 3-hydroxychinolin-2,4(1H,3H)-dionů na titulní slou-čeniny užitím chlor(fenyl)acetylchloridu jako reakčního činidla. Titulní sloučeniny byly podrobeny působení trifenylfosfanu v p-cymenu za zvýšené teploty a produkty byly sepa-rovány sloupcovou chromatografií. V některých případech byly izolovány 1-fenylfuro[2,3-c]chinolin-2,4(3aH,5H)-diony, které se tvoří intramolekulární Wittigovou reakcí z ylidů vznikajících rozkladem primárně vzniklých fosfoniových solí. Výchozí 3-hydroxychinolin-2,4(1H,3H)-diony byly připraveny dvoustupňovou syntézou vycházející z kondenzace ani-linů s diethyl-malonáty a následnou oxidací vzniklých sloučenin. |
cs |
| dc.format |
61 s. |
cs |
| dc.format.extent |
1776336 bytes |
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| dc.format.mimetype |
application/pdf |
cs |
| dc.language.iso |
cs |
|
| dc.publisher |
Univerzita Tomáše Bati ve Zlíně |
|
| dc.rights |
Bez omezení |
|
| dc.subject |
3-hydroxychinolin-2
|
cs |
| dc.subject |
4
|
cs |
| dc.subject |
1H
|
cs |
| dc.subject |
3H-dion
|
cs |
| dc.subject |
2
|
cs |
| dc.subject |
4-dioxo-1
|
cs |
| dc.subject |
2
|
cs |
| dc.subject |
3
|
cs |
| dc.subject |
4-tetrahydrochinolin-3-yl?chlor
|
cs |
| dc.subject |
fenyl-acetát
|
cs |
| dc.subject |
chlor
|
cs |
| dc.subject |
fenylacetyl-chlorid
|
cs |
| dc.subject |
1-fenylfuro[2
|
cs |
| dc.subject |
3-c]chinolin-2
|
cs |
| dc.subject |
4-dion
|
cs |
| dc.subject |
Wittigova reakce
|
cs |
| dc.subject |
3-hydroxyquinoline-2
|
en |
| dc.subject |
4
|
en |
| dc.subject |
1H
|
en |
| dc.subject |
3H-dione
|
en |
| dc.subject |
2
|
en |
| dc.subject |
4-dioxo-1
|
en |
| dc.subject |
2
|
en |
| dc.subject |
3
|
en |
| dc.subject |
4-tetrahydroquinoline-3-yl?chlorine
|
en |
| dc.subject |
phenylacetate
|
en |
| dc.subject |
chlorine
|
en |
| dc.subject |
phenylacetylchloride
|
en |
| dc.subject |
1-phenylfuro[2
|
en |
| dc.subject |
3-c]quinoline-2
|
en |
| dc.subject |
4
|
en |
| dc.subject |
3aH
|
en |
| dc.subject |
5H-dione
|
en |
| dc.subject |
Wittig reaction
|
en |
| dc.title |
2,4-Dioxo-1,2,3,4-tetrahydrochinolin-3-yl-chlor(fenyl)acetáty a produkty jejich reakce s trifenylfosfanem |
cs |
| dc.title.alternative |
2,4-Dioxo-1,2,3,4-Tetrahydroquinolin-3-yl-Chloro(phenyl)acetates and Products of their Reaction with Triphenylphosphane |
en |
| dc.type |
diplomová práce |
cs |
| dc.contributor.referee |
Potáček, Milan |
|
| dc.date.accepted |
2012-06-12 |
|
| dc.description.abstract-translated |
The thesis describes the method of conversion of 3-hydroxyquinoline-2,4(1H,3H)-dione in the title compounds by using chlorine(phenyl)acetylchloride as a reagent. Title compounds were subjected to the exposure of triphenylfosfane in p-cymene at elevated temperatures and the products were separated by column chromatography. In some cases were isolated 1-phenylfuro[2,3-c]quinoline-2,4(3aH,5H)-diones, which are formed by intramolecular Wittig reaction of ylides generated primarily due to the decomposition of phosphonium salts. Default 3-hydroxyquinoline-2,4(1H,3H)-diones were prepared by two-step synthesis based on the condensation of anilines with diethyl Malone and subsequent oxidation of the resulting compounds. |
en |
| dc.description.department |
Ústav chemie |
cs |
| dc.description.result |
obhájeno |
cs |
| dc.parent.uri |
http://hdl.handle.net/10563/199
|
cs |
| dc.parent.uri |
http://hdl.handle.net/10563/220
|
cs |
| dc.thesis.degree-discipline |
Chemie potravin a bioaktivních látek |
cs |
| dc.thesis.degree-discipline |
Food Chemistry and Chemistry of Bioactive Substances |
en |
| dc.thesis.degree-grantor |
Univerzita Tomáše Bati ve Zlíně. Fakulta technologická |
cs |
| dc.thesis.degree-grantor |
Tomas Bata University in Zlín. Faculty of Technology |
en |
| dc.thesis.degree-name |
Ing. |
cs |
| dc.thesis.degree-program |
Chemie a technologie potravin |
cs |
| dc.thesis.degree-program |
Chemistry and Food Technologies |
en |
| dc.identifier.stag |
27645
|
|
| utb.result.grade |
C |
|
| dc.date.submitted |
2012-05-07 |
|
